Integrated Models for the Development and Assessment of High Impact Chemicals and Materials

Today, the new HorizonEurope-funded project INSIGHT – Integrated Models for the Development and Assessment of High Impact Chemicals and Materials starts its ambitious R&I (research and innovation) programme.

Over the next 48 months 20 partners from 18 countries all over the globe will overcome the challenges that are currently hampering the emergence of a comprehensive approach to safe and sustainable by design (SSbD) chemicals and materials, by developing an innovative framework for mechanistic impact assessment of chemicals/materials:

Illustration of the geographic spread of the INSIGHT consortium; the Project spans across Europe and has members in North & South America, Asia and Oceania.

The INSIGHT framework will consist of a multi-layered approach that integrates data, models, and impact outcome pathway (IOP) graphs. INSIGHT will also provide curated and user-friendly FAIR data and computational models/workflows. INSIGHT aims to foster a paradigm shift in the assessment of sustainability and safety of chemicals and materials, from a fragmented situation to a holistic and integrated approach. INSIGHT will provide decision maps as a part of its integrated framework to guide users through the decision-making process, aiding them in evaluating the social, economic, health and environmental impacts of chemicals/materials in a more efficient and comprehensive manner.
By democratising the use of cutting-edge AI methods to SSbD, INSIGHT will drive innovation towards a digital, circular, climateneutral and sustainable economy. INSIGHT will help the industry to optimise development and production of chemicals/materials and derived products, support regulators and policymakers in informed decision-making towards safer and more sustainable society, and pave the way for a comprehensive approach to
SSbD.